Description

Job Description

General Summary:

As a key strategic leader in Global Clinical Operations (GCO), the Senior Director, Digitization Strategy Center of Excellence is responsible for driving the implementation of transformation initiatives that enhance clinical trial and development operations within GCO and across cross functional GMDA collaborators. The Senior Director will enable the acceleration of trial and developmental milestones on high priority pipeline diseases (e.g. T1D, Kidney, Pain and CF) through relevant, effective and optimized end to end trial operations processes, driving a digital and systems strategy and enabling capabilities with a focus on innovation (e.g. digitization, AI/ML). This role is responsible for enabling the generation of data, insights and analytics to drive decision making across GCO and broader GMDA functions. The ideal candidate will bring deep expertise in clinical operations, relevant disease areas and proven track record of designing and implementing transformative AI/ML strategies to identify opportunities for optimization and acceleration across the trial lifecycle. This role will use a combination of data, analytics and process optimization to drive performance excellence and business transformation for GCO. The Senior Director will partner with global stakeholders to embed transformations into development processes, optimize efficiency, and enable data-driven decision-making while maintaining compliance and ethical standards. By building and leading a high-performing team, this leader fosters a culture of continuous improvement and capability building, ensuring the organization is future-ready and equipped to deliver impactful transformation

Key Duties and Responsibilities:

• Lead the strategy, design, digitization, implementation, and continuous improvement of global clinical operations end to end processes to identify opportunities to drive value (e.g. increased efficiencies, reduction of manual work effort, trial cost optimization).
• Design and lead high-impact strategic transformation initiatives and priorities, with a focus on enabling business impact through well-designed change management and process re-design
• Partner with GCO program teams and GMDA teams to define innovations to support disease strategies and capabilities across Vertex disease areas (e.g. AI-enabled patient finding, trial site identification, predictive modeling)
• Option - Take charge of the Advanced Analytics capabilities, building a strong team over time, to enable real-time insights through AI-driven models, self-service analytics, and predictive intelligence to drive trial operational excellence.
• Develop and partner to execute on multi-year roadmap for GCO, including evaluating, implementing and optimizing strategic clinical trial solutions/tools to enhance automation, enable data driven decision-making and create simplified and orchestrated user experiences.
• Collaborate across the GCO team to develop value delivery plans, goals, and metrics linked to business objectives including articulating relevant value for transformation initiatives (e.g. time savings, cost, NPV)
• Leverage external insights from digital health, AI, and professional networks to inform capability-building, solution prioritization, and future-ready operations
• Identify repeatable transformation capabilities to drive business process simplification and enhance productivity to achieve cost efficiencies across trial lifecycle
• Partner with trial vendors and internal team members to test and validate new transformative solutions, ensuring change management and process transformation is in place to drive impact
• Drive AI-enabled process simplification initiatives to achieve efficiencies across GCO
• Define success metrics and track ROI for transformation initiatives, demonstrating tangible business value including speed, quality, and cost
• Option - Lead change management efforts to embed AI-enhanced data & analytics capabilities into strategic decision-making, ensuring agility and scalability
• Build training and enablement programs to upskill teams and foster confidence in AI-driven processes
• Serve as a trusted advisor to GCOLT and GMDA Leaders, articulating the business case for transformation initiatives
• Communicate progress, impact, and lessons learned across the organization to maintain transparency and momentum

Education and Experience:

• 10+ years of experience in Clinical Operations roles
• 10+ years of experience in driving analytics, AI, and technology initiatives
• Demonstrated expertise in change management methodologies and organizational transformation
• Proven ability to translate innovation strategies into operational execution and business impact
• Expertise in developing disease specific data strategies
• Proven track record of implementing advanced technologies to enhance and optimize clinical operations teams
• Exceptional leadership, communication, and stakeholder management skills

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Pay Range:
$216,000 - $324,000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:
Remote-Eligible

Flex Eligibility Status:

In this Remote-Eligible role, you can choose to be designated as:
1. Remote: work remotely five days per week and come into the office on occasion - you're always welcome on-site; or select
2. Hybrid: work remotely up to two days per week; or select
3. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

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Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com